10 pit stops to make on a road trip along I-10 from Arizona to New Mexico

Don’t overlook this stretch of interstate filled with spicy wine, alien history, underground caves, and plenty of desert landscapes

A road trip across Arizona may instantly conjure up images of Route 66, which cuts across the northern section of the state from east to west, but there’s another major thoroughfare that shouldn’t be overlooked—Interstate 10. This highway runs the length of the U.S., but a particular stretch between Tucson, Arizona, and Las Cruces, New Mexico, offers a pleasing mix of historic sites, state and national parks, and kitschy, gram-worthy stops.

Here are 10 stops to make on a fun-filled west-to-east road trip along I-10.

Saguaro cacti stand amid prickly shrubs in Arizona
Saguaro National Park, West District. | Photo: Erin Gifford

1. Tucson Mountain District, Saguaro National Park (West)

Saguaro National Park is home to the country’s largest cactus, the saguaro, which can grow to more than 40 feet tall. This park has two districts, East and West, which sit on either side of Tucson. The West side, also known as the Tucson Mountain District, is the more popular of the two, due largely to its greater density of tree-like cacti.

At the Red Hills Visitor Center, stop for a short park film, then drive the 6-mile Scenic Bajada Loop Drive. Easy hikes along the loop include the Valley View Overlook Trail, which wows with big views across Tucson, as well as the scenic Signal Hill Trail, which leads to ancient petroglyphs. 

A prickly cactus garden at the Arizona-Sonora Desert Museum
Cactus Garden at the Arizona-Sonora Desert Museum. | Photo: Erin Gifford

2. Arizona-Sonora Desert Museum  

The beauty of the Sonoran Desert is on full display at the Arizona-Sonora Desert Museum in Tucson. This 98-acre outdoor museum is home to native animal species like river otters, javelinas, and Mexican gray wolves. Stroll the Cactus Garden for dozens of cactus varieties, including cholla, prickly pear, and organ pipe cactus. On warm days, children can play in the air-conditioned Packrat Playhouse, an award-winning indoor play space with slides and climbing structures.

A close-up view of an airplane at Pima Air & Space Museum
Pima Air & Space Museum. | Photo: Erin Gifford

3. Pima Air & Space Museum 

The Pima Air & Space Museum in Tucson is one of the largest non-government funded aviation museums in the world. Nearly 400 aircraft of all sizes are on display, both inside large hangars and outside on the massive air field. Stroll or take a tram tour across the 80-acre grounds to ogle retired military cargo planes, commercial aircraft, and even presidential airplanes. Several planes on display in the air field have been turned into contemporary works of art as part of the Boneyard Project. 

Purple wildflowers at Saguaro National Park, East District
Saguaro National Park, East District. | Photo: Erin Gifford

4. Rincon Mountain District, Saguaro National Park (East)

The East district of Saguaro National Park is replete with cactus, though there are fewer to see on this side of the park. The Rincon Mountain Visitor Center is a good starting point ahead of a drive along the 5-mile Cactus Forest Drive, a scenic loop that affords plentiful views of saguaros. Easy trails include the Desert Ecology Trail and Freeman Homestead Trail, both of which use placards to educate on the wonders of the Sonoran Desert—note that Cactus Forest Drive is one-way and is popular with bicyclists on weekends. 

People ride horses past saguaro cacti in Colossal Cave Mountain Park
Colossal Cave Mountain Park. | Photo courtesy of Visit Tucson

5. Colossal Cave Mountain Park

Colossal Cave Mountain Park in nearby Vail, Arizona, is a natural wonder that’s home to one of the largest dry caves in the U.S. The cave system has 3.5 miles of mapped passages. Tours guide visitors along a half-mile stretch to view unique formations, like stalactites and stalagmites. There’s more to see beyond underground caverns, too. The park offers opportunities for hiking, biking, horseback riding, and camping. An on-site café sells craft beers, wines, and snacks. 

Inside a cave at Kartchner Caverns State Park stalagmites and stalactites make for an impressive scene
Kartchner Caverns State Park. | Photo courtesy of Visit Tucson

6. Kartchner Caverns State Park 

For more caves, look to Kartchner Caverns State Park in Benson, Arizona. Several cavern tours set off daily (reservations are encouraged), including a helmet and headlamp tour that allows visitors to experience the cave as explorers did in 1974. On terra firma, hike trails, stroll in the Hummingbird Garden, and view native wildlife, like tortoises, lizards, and cottontail rabbits. Kids ages 6 to 12 years old can complete an activity booklet to become a Junior Ranger. Make it a weekend with a stay at the on-site campground, which has tent and RV sites as well as cabins.

A wooden sign reads "Old Tombstone Western Town"
Tombstone Historic District. | Photo: Erin Gifford

7. Tombstone Historic District 

Less than 30 minutes off I-10 is the Old Western town of Tombstone, Arizona, which brims with gunslinging history. Officially the Tombstone National Historic District, there’s a lot to learn about the Wild West across this three-block town. Go underground to explore the Good Enough Silver Mine, take a self-guided tour of the Boothill Graveyard, and visit the O.K. Corral. On Allen Street, dramatic gunfight reenactments take place several times each day. 

A quirky "aliens vs. dinosaurs" exhibit at The Thing Travel Center in Arizona
Bowlin’s The Thing Travel Center. | Photo: Erin Gifford

8. The Thing Travel Center

Bowlin’s The Thing Travel Center (aka The Thing Museum) is a quirky roadside attraction in Benson, Arizona, advertised by dozens of signs up and down I-10 between El Paso, Texas, and Tucson. For an entry fee of $5, you’ll leave with a headful of conspiracy theories that revolve around alien life forms. Without giving away too much, you may learn that aliens allegedly had a hand in everything from the extinction of dinosaurs to World War II. It’s worth a walk through, if only to see “The Thing” itself, encased in glass at the end of the attraction. There’s also an on-site gift shop and a Dairy Queen. 

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Striking rock formation rise into the sky at Chiricahua National Monument
Chiricahua National Monument. | Photo courtesy of Visit Tucson

9. Chiricahua National Monument 

Located in Wilcox in Southeast Arizona, Chiricahua National Monument has been called the “Wonderland of Rocks.” It’s so magnificent that federal legislation has been introduced to grant it national park status; if it passes, Chiricahua would become Arizona’s fourth national park. The park has hiking trails that range from easy nature walks to strenuous multi-mile hikes. A scenic drive takes visitors to the historic Faraway Ranch and up to stunning vistas at Massai Point, which offers an easy hike on the Massai Point Nature Trail. Echo Canyon Grottoes and Inspiration Point are popular for rock formations and big views. 

Green chilis are stacked up at a market
Green chiles for tasting on the Walk of Flame. | Photo courtesy of Visit Las Cruces

10. Walk of Flame

The last stop on I-10 is a bit of a drive, but your taste buds will thank you as you explore the green chile-laced foods, drinks, and experiences along the Walk of Flame in Las Cruces. This delectable green chile trail allows visitors to experience green chiles in traditional favorites, like soups and tacos, but also on ice cream, hot dogs, and even in wine. The Walk of Flame has stops all across town, including a food truck called the Green Chile Paddy Wagon, so visitors can savor the green chile flavor. Take a tour of the Chile Pepper Institute Teaching Garden at New Mexico State University, which has more than 150 varieties of chile peppers.  

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